Redd Foxx played Sanford as a sarcastic, stubborn, and argumentative antiques and junk dealer, whose frequent money-making schemes routinely backfired and created more troubles. Lamont dearly would have liked to enjoy independence but loved his father too much to leave him to his devices and schemes. Although each owned an equal share in the business and technically Fred was the boss, Lamont often found himself doing all the work and having to order his father to complete tasks and duties.

On the show’s premiere in 1972, newspaper ads touted Foxx as NBC’s answer to Archie Bunker, the bigoted white protagonist of All in the Family. (Both shows were adapted by Norman Lear from BBC shows.)

Fred Sanford was a widower (he had moved to Los Angeles from St. Louis), whose wife Elizabeth had died some two decades before. Fred had raised Lamont alone and missed Elizabeth deeply. According to Fred, his son was named for Lamont Lomax, a (presumably fictional) pitcher from the Homestead Grays. At first, Fred’s main foil on the show was in his sister-in-law and Lamont’s aunt, Ethel (Beah Richards). Ethel’s involvement in the Sanford family squabbles lasted only until midway through the second season, whereupon she was replaced with her more tart-tongued sister, Esther (LaWanda Page). Fred and Esther’s relationship as in-laws went on to become a major part of the series’ legend, as Fred loved to put down Esther on a regular basis with a burning passion. Esther’s disdain for Fred stemmed back to when he and Elizabeth were dating; she had disapproved of Fred marrying her sister. He would often contort his face upon Esther’s entrance and make disparaging remarks to her, comparing her with King Kong and Godzilla and using colorful metaphors to describe her. Despite his stubbornness, Fred would sometimes redeem himself with acts of kindness, even to those (like Esther) who he insists he doesn’t like. In the last episode of the series, Fred earned his high school diploma, and was the valedictorian of his graduating class.

Earlier in the show’s run, it adhered more closely to the format laid out by its British predecessor, Steptoe and Son, with Fred and Lamont often at loggerheads over various issues. Fred and Lamont were also depicted as being equally manipulative (Fred with his constant threats of “the big one” and his “arthur-itis”; Lamont with his attempts to drive a wedge between Fred and his girlfriend, Donna, who he saw as usurping his mother’s place). At times, Lamont was actually depicted as the greedier of the two; for example, in one episode he refused to sell two coffins for less than what he thought they were worth, despite the fact that they clearly upset his somewhat superstitious father. As well, Lamont sometimes received his comeuppance for being disdainful of his father’s habits and ways (an example of this would be the time Lamont was upbraided by a Nigerian woman he hoped to impress by “adopting” African culture; she considered his attitude towards Fred to be disrespectful). There were even moments when Lamont was shown to be naive and foolish, such as the episode where he invited his new “friends” over to play poker; his more experienced father saw right away that they were actually out to cheat Lamont, after they had gained his confidence by letting him win a few smaller-stakes games.

As the series progressed, however, it became more focused on Fred’s antics and schemes, with Lamont often adopting the role of the gentler, more open-minded progressive who attempted to broaden his father’s horizons. A notable example of the softening of Lamont’s character is his change in attitude towards Donna Harris (Lynn Hamilton), Fred’s girlfriend; early in the show’s run, Lamont derided her as “the barracuda” and was openly hostile towards her (to say nothing of attempting to ruin her relationship with his father at least twice), yet an episode later in the series’ run saw Lamont inviting Donna out to dinner with himself and his girlfriend, remarking that it would do his reputation good to be seen with “two lovely ladies”. Similarly, Fred was initially depicted as a man who, if not always ethically or culturally sensitive, had the wisdom of experience. As the show went on, Fred was seen getting into increasingly ludicrous situations, such as faking a British accent to get a job as a waiter; convincing a white couple that an earthquake was really the “Watts subway”; taking over a play featuring George Foreman; or sneaking into a celebrity’s private area, such as Lena Horne’s dressing room or Frank Sinatra’s hotel room. Many of these situations invariably revolved around Fred trying to make a quick buck.

One constant remained through the show, however, and that was the loyalty of father and son to each other. Even in the show’s earliest episodes when one or the other left the house, seemingly for good (Lamont moved out at least twice, and at one point he even put Fred in an old folks’ home), something always occurred that returned things back to normal (Lamont got homesick and worried about his father, or something didn’t work out and Lamont schemed his way back in; Lamont felt lonely without his father around the house thanks to a plan Bubba and Fred hatched). Perhaps the best example of this bond between father and son occurred in the episode where a friend from Fred’s past showed up and claimed to be Lamont’s real father. After hearing the news, Lamont told a tearful Fred that he was “the only pop I’ve ever had” and as far as he was concerned, it was “always” going to be Sanford and Son (in the humorous twist that closed the episode, it turned out the friend had accidentally slept with Aunt Esther, thinking she was her sister Elizabeth).

Sanford and Son was enormously popular during most of its run, and was one of the top ten highest-rated series on American television from its first season (1971-72) through the 1975-76 season. With its coveted 8pm Eastern Friday night time slot, Sanford and Son put enough of a dent into the middling audience of ABC’s The Brady Bunch to drive it off the air in 1974. Sanford and Son peaked at #2 in the Nielsen ratings during the 1973-74 season, and stayed there for three years in a row. The series was second only to All in the Family in terms of ratings. The show was still quite popular when it was cancelled (due entirely to Foxx’s departure from the show) in 1977.

In 2007, Time magazine included the show on their list of the “100 Best TV Shows of All Time”.